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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK11
All Species:
7.58
Human Site:
S574
Identified Species:
16.67
UniProt:
Q8NG66
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NG66
NP_001139475.1
645
74162
S574
K
M
K
R
M
R
E
S
A
M
Q
K
L
G
T
Chimpanzee
Pan troglodytes
XP_001146942
470
54021
E401
K
T
H
L
K
G
M
E
E
K
E
E
Q
P
E
Rhesus Macaque
Macaca mulatta
XP_001115725
637
73261
K567
N
S
V
M
A
R
T
K
M
K
R
M
R
E
S
Dog
Lupus familis
XP_542780
746
83424
R677
K
V
Y
N
Y
L
K
R
A
R
R
Q
K
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0Q4
628
71648
R558
E
V
Y
D
Y
L
K
R
A
R
R
Q
N
A
R
Rat
Rattus norvegicus
NP_001101652
507
57337
V438
E
I
P
E
D
P
L
V
A
E
Q
Y
Y
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514341
605
69266
S532
R
M
K
R
M
R
E
S
A
I
Q
K
L
G
A
Chicken
Gallus gallus
XP_414252
807
90823
S718
T
L
V
L
H
G
K
S
P
E
E
S
E
D
F
Frog
Xenopus laevis
Q7ZZC8
944
104521
T813
E
S
S
Q
N
G
T
T
S
M
Q
D
V
R
E
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
G626
G
I
T
M
A
A
C
G
D
A
F
T
L
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
R530
A
T
A
G
A
S
S
R
A
S
S
G
V
R
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.4
94.1
69
N.A.
72.5
57.8
N.A.
67.9
27.1
20.7
23.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
72.5
95.9
75.4
N.A.
81
67.9
N.A.
78.2
46.7
38.9
42.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
13.3
N.A.
6.6
13.3
N.A.
80
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
46.6
N.A.
40
26.6
N.A.
93.3
26.6
46.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
28
10
0
0
55
10
0
0
0
37
10
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
10
0
0
0
10
0
0
10
0
10
10
% D
% Glu:
28
0
0
10
0
0
19
10
10
19
19
10
10
10
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% F
% Gly:
10
0
0
10
0
28
0
10
0
0
0
10
0
19
0
% G
% His:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
0
0
0
0
0
0
0
10
0
0
0
0
10
% I
% Lys:
28
0
19
0
10
0
28
10
0
19
0
19
10
0
0
% K
% Leu:
0
10
0
19
0
19
10
0
0
0
0
0
28
0
0
% L
% Met:
0
19
0
19
19
0
10
0
10
19
0
10
0
0
0
% M
% Asn:
10
0
0
10
10
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
10
0
0
10
0
0
10
0
0
0
0
10
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
37
19
10
0
0
% Q
% Arg:
10
0
0
19
0
28
0
28
0
19
28
0
10
19
19
% R
% Ser:
0
19
10
0
0
10
10
28
10
10
10
10
0
0
19
% S
% Thr:
10
19
10
0
0
0
19
10
0
0
0
10
0
0
10
% T
% Val:
0
19
19
0
0
0
0
10
0
0
0
0
19
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
19
0
19
0
0
0
0
0
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _